TEDDY publications

So far, the TEDDY Network has produced more than 50 publications, that vary widely in focus and theme.

The TEDDY publication policy is an important evidence of the Network’s commitment in the field of paediatric high-level scientific information.

TEDDY members have still continued to work together to favour awareness on the topics of paediatric research and to spread information on the rational use of paediatric medicines to identify unmet medical needs in paediatrics.

Here is the list of TEDDY Network publications:

TEDDY Network Publications


Lupo M., Intini A., Filannino D. Informed Participation and Patient Empowerment: A Patient-Centered Approach to Improve Pediatric Clinical Research. The Management of Clinical Trials, 978-1-78923-239-4; Publisher: Intech, June, 6th 2018. Available at: https://www.intechopen.com/books/the-management-of-clinical-trials/informed-participation-and-patient-empowerment-a-patient-centered-approach-to-improve-pediatric-clin

Chiaruttini G., Felisi M. and Bonifazi D. Challenges in Paediatric Clinical Trials: How to Make It Feasible. The Management of Clinical Trials, 978-1-78923-239-4; Publisher: Intech, June, 6th 2018. Available at: https://www.intechopen.com/books/the-management-of-clinical-trials/challenges-in-paediatric-clinical-trials-how-to-make-it-feasible

Alcobendas R, Remesal A, Murias S, Nuñez E, Calvo C. Outpatients with acute osteoarticular infections had favourable outcomes when they received just oral antibiotics without intravenous antibiotics. Acta Paediatr. 2018 Apr 29. doi: 10.1111/apa.14373. [Epub ahead of print] PMID: 29705992. Available at: https://onlinelibrary.wiley.com/doi/abs/10.1111/apa.14373

Martín Del Valle F, Calvo C, Martinez-Rienda I, Cilla A, Romero MP, Menasalvas AI, Reis-Iglesias L, Roda D, Pena MJ, Rabella N, Portugués de la Red MDM, Megías G, Moreno-Docón A, Otero A, Cabrerizo M; Grupo de Estudio de las infecciones por enterovirus y parechovirus en niños. Epidemiological and clinical characteristics of infants admitted to hospital due to human parechovirus infections: A prospective study in Spain. An Pediatr (Barc). 2018 Feb;88(2):82-88. doi: 10.1016/j.anpedi.2017.02.009. Epub 2017 Mar 30. Spanish. PMID: 28365283. Available at: https://www.ncbi.nlm.nih.gov/pubmed/28365283


Garcia-Garcia ML, Calvo C, Ruiz S, Pozo F, Del Pozo V, Remedios L, Exposito N, Tellez A, Casas I. Role of viral coinfections in asthma development. PLoS One. 2017 Dec 5;12(12):e0189083. doi: 10.1371/journal.pone.0189083. eCollection 2017. PMID: 29206851. Available at: https://www.ncbi.nlm.nih.gov/pubmed/29206851

Veal GJ, Malik S, Lupo M, MacFarlane S, Lepola P, Costello M, Ceci A, Boué C, Lecour C, Otto A, Rastegari M, Berry P. Investigating the roles and training of paediatric research nurses working across Europe: a questionnaire-based survey.BMJ Paediatr Open. 2017 Sep 5;1(1):e000170. doi: 10.1136/bmjpo-2017-000170.eCollection2017. http://bmjpaedsopen.bmj.com/content/1/1/e000170

García-García ML, Calvo C, Moreira A, Cañas JA, Pozo F, Sastre B, Quevedo S, Casas I, del Pozo V. Thymic Stromal Lymphopoietin, IL-33 and periostin in hospitalized infants with viral bronchiolitis. Medicine (Baltimore). 2017 May;96(18):e6787. Available at: https://www.ncbi.nlm.nih.gov/pubmed/28471975

Giannuzzi V, Devlieger H, Margari L, Odlind VL, Ragab L, Bellettato CM, D’Avanzo F, Lampe C, Cassis L, Cortès-Saladelafont E, Cazorla ÁG, Barić I, Cvitanović-Šojat L, Fumić K, Dali CI, Bartoloni F, Bonifazi F, Scarpa M, Ceci A. The ethical framework for performing research with rare inherited neurometabolic disease patients. European Journal of Pediatrics. 2017 Mar; 176(3):395-405.  Epub 2017 Jan 16. https://link.springer.com/article/10.1007%2Fs00431-017-2852-9

Garcìa ML, Calvo C, Rey C, Dìaz B, Molinero M, Pozo F, Casas I (2017). Human metapnuemovirus infections in hospitalized children and comparison with other respiratory viruses. 2005-2014 prospective study. PLoS ONE 12(3): e0173504. https://doi.org/10.1371/journal. pone.0173504


Paola D’andria, Viviana Giannuzzi, Fedele Bonifazi, Adriana Ceci, Nunzio Denora, Cosimo D. Altomare. Formulating medicines for children: challenges and issues. DOI: http://dx.medra.org/10.17374/CI.2016.98.3.4


Ceci A, Giannuzzi V, Bonifazi D, Felisi M, Bonifazi F and Ruggieri L Clinical Trials in Paediatrics — Regulatory and Methodological Aspects. Drug Discovery and Development – From Molecules to Medicine, Prof. Omboon Vallisuta (Ed.), ISBN: 978-953-51-2128-2, InTech, DOI: 10.5772/60611. Available at: http://www.intechopen.com/books/drug-discovery-and-  development-from-molecules-to-medicine/clinical-trials-in-paediatrics-  regulatory-and-methodological-aspects

Giannuzzi V, Altavilla A, Ruggieri L, Ceci A. Clinical Trial Application in Europe: What Will Change with the New Regulation? Sci Eng Ethics. 2015 Jun 3. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/26037896

Ruggieri L, Giannuzzi V, Baiardi P, Bonifazi F, Davies EH, Giaquinto C, Bonifazi D, Felisi M, Chiron C, Pressler R, Rabe H, Whitaker MJ, Neubert A, Jacqz-Aigrain E, Eichler I, Turner MA, Ceci A; GRiP Consortium. Successful private-public funding of paediatric medicines research: lessons from the EU programme to fund research into off-patent medicines. Eur J Pediatr. 2015 Apr;174(4):481-91. doi: 10.1007/s00431-014-2398-z. Epub 2014 Sep 23



Piñeiro Péreza R, Ruiz Antoránb MB, Avendaño Solá C, Román Riechmann E, Cabrera García L, Cilleruelo Ortega ML, Mellado Peña MJ. Conocimiento sobre el uso de fármacos off-label en Pediatría. Resultados de una encuesta pediátrica nacional 2012-2013 (estudio OL-PED). An Pediatr (Barc). 2014; 81(1):16-21. Avalaible at: http://www.analesdepediatria.org/es/conocimiento-sobre-el-uso-  farmacos/articulo/S1695403313004086/

Piñeiro Pérez R, Martínez Fernández-Llamazares C, Calvo Rey C, Piñeiro Pérez AP, Criado Vega EA, Bravo Acuña J, Cabrera García L, Mellado Peña MJ Asociación Española de Pediatría, Pediamécum: un año de experiencia. An Pediatr (Barc). 2014;81(4):257.e1-257.e6. Available at: http://analesdepediatria.org/es/pediamecum-un-ano-  experiencia/articulo/S1695403314001015/